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Asymptomatic Bacteriuria in Older Adults – Diagnosis, Management, and Future Directions: A Narrative Review
Ki Hong Kim, Hee Jo Yang
Urogenit Tract Infect 2025;20(2):58-66.   Published online August 31, 2025
DOI: https://doi.org/10.14777/uti.2550002001
AbstractAbstract PDFPubReader
Asymptomatic bacteriuria (ASB) is defined as the presence of bacteria in the urine in the absence of urinary tract infection (UTI) symptoms. The prevalence of ASB increases with advancing age, particularly among older patients with underlying health conditions. ASB is especially common among residents of long-term care facilities; however, distinguishing ASB from symptomatic UTI in this population remains a significant clinical challenge. The frequent occurrence of ASB often results in unnecessary antibiotic administration, thereby contributing to the development of antibiotic resistance. Current clinical guidelines recommend screening for and treating ASB only in certain circumstances, such as prior to urological procedures or in pregnant women. There is a pressing need for improved diagnostic approaches to differentiate ASB more accurately from UTI, particularly in older adults. Reducing unnecessary urine testing and inappropriate antibiotic use may help prevent over-treatment and minimize associated risks, including Clostridium difficile infection and increased antimicrobial resistance.

Citations

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  • Effect of systemic enzyme therapy on the incidence of stentassociated infectious complications in female patients with urolithiasis: a multicentre study
    S. V. Kotov, A. A. Nemenov, R. A. Perov, I. E. Mamaev, S. V. Belomyttsev, S. A. Pulbere, A. D. Bolotov
    Urology Herald.2026; 14(2): 56.     CrossRef
  • In Vitro Activity of Mecillinam Against ESBL- and Non-ESBL-Producing Escherichia coli and Klebsiella pneumoniae Urinary Isolates
    Alvaro Irigoyen-von-Sierakowski, Ramón Pérez-Tanoira, Pilar Galicia, Manuel Linares-Rufo, María Ropero-Martínez, Harold Bermúdez-Marval, Carlos García-Bertolín, José Vázquez-Mariño, Juan Cuadros-González
    Acta Microbiologica Hellenica.2026; 71(3): 33.     CrossRef
  • Association Between Asymptomatic Bacteriuria and Adverse Pregnancy and Birth Outcomes
    Batool Munhim Jubair, Zainab Tariq Alyassin
    Clinical Medicine and Health Research Journal.2026; 06(05): 1908.     CrossRef
  • Evaluation of Extended-Spectrum Beta-Lactamase Production and 28-Day Mortality Predictors in Urine Cultures of Hospitalized Elderly Patients
    Kerem Yılmaz, Merve Büyükkörük, Akın Öğünç İnan
    Urologia Internationalis.2026; : 1.     CrossRef
  • Diagnostic Accuracy and Variability in Positivity Criteria of Genomic Methods for Urinary Tract Infection: A Systematic Review and Meta-Analysis
    Maryam Jawad, Fatima Wasif Dar, Fatmaelzahraa Gamil Omar, Zaina Asif Hussain, Marfoha Tabassum, Osama Ahmed, Amal A. H. Gadalla
    Antibiotics.2026; 15(11): 1093.     CrossRef
  • Editorial for Urogenital Tract Infection (UTI) 2025 Vol. 20 No. 2 – Highlights of This Issue’s Papers and the UTI Editors’ Pick
    Koo Han Yoo
    Urogenital Tract Infection.2025; 20(2): 55.     CrossRef
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Postoperative Microscopic Pyuria and Role of Damage-Associated Molecular Pattern: A Literature Review
Min-Kyu Kim, Ki Hong Kim
Urogenit Tract Infect 2024;19(3):73-79.   Published online December 31, 2024
DOI: https://doi.org/10.14777/uti.2448026013
AbstractAbstract PDFPubReaderePub
All patients who undergo transurethral prostate surgery exhibit pyuria and microscopic hematuria in postoperative urinalysis. Postoperative asymptomatic pyuria is associated with the inflammatory process and surface remodeling of the prostate, rather than infection. Various studies have investigated the incidence, duration, and risk factors for postoperative pyuria, noting that factors like age, surgery time, and prostate size can influence outcomes. Postoperative pyuria reflects tissue recovery and inflammation, and the use of antibiotics in asymptomatic patients may not be appropriate.
  • 10,950 View
  • 41 Download
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