Urogenital Tract Infection

Table. 2.

Comparative characteristics of patients with and without sepsis

Variables Sepsis (−) (n=229) Sepsis (+) (n=14) p-value
Age (y) 59.0 (14-90) 52.5 (21-87) 0.178
BMI (kg/m2) 24.7 (14.3-48.2) 23.2 (20.0-31.5) 0.542
Sex 0.387
Male 120 (52.4) 9 (64.3)
Female 109 (47.6) 5 (35.7)
Underlying disease
HTN 111 (48.5) 6 (42.9) 0.683
DM 65 (28.4) 5 (35.7) 0.557
IHD 9 (3.9) 1 (7.1) 0.454
CVA 22 (9.6) 2 (14.3) 0.636
CKD 20 (8.7) 2 (14.3) 0.368
Medical history Hx.
Stone Hx. 72 (31.4) 4 (28.6) 1
UTI Hx. 11 (4.8) 3 (21.4) 0.038*
Antithrombotic agent 43 (18.8) 2 (14.3) 1
Preoperative antibiotics 90 (39.3) 8 (57.1) 0.186
Stone
Size (mm) 9.00 (2.00-35.0) 10.2 (3.00-40.0) 0.241
Location (main) 0.366
Upper pole 35 (15.3) 1 (7.1)
Mid pole 43 (18.8) 2 (14.3)
Lower pole 70 (30.5) 8 (57.1)
Pelvis 54 (23.6) 3 (21.4)
UPJ or Proximal ureter 27 (11.8) 0 (0.0)
RIRS
Operation time (min) 60 (12-227) 107 (35-229) 0.004*
Laterality 0.181
Left 106 (46.3) 5 (35.7)
Right 88 (38.4) 4 (28.6)
Both 35 (15.3) 5 (35.7)
Preoperative drainage
Ureteral stent 58 (25.3) 5 (35.7) 0.389
PCN 11 (4.8) 0 (0.0) 1
None 160 (69.9) 9 (64.3)
Balloon dilation 0.028*
Yes 18 (7.9) 4 (28.6)
No 211 (92.1) 10 (71.4)
Operative techniques 0.09
Dusting only 1 (0.4) 1 (7.1)
Basketing only 27 (11.8) 2 (14.3)
Both 201 (87.8) 11 (78.6)
Preoperative culture
Positive urine culture 54 (23.6) 8 (57.1) 0.005*
Bacteremia 14 (6.1) 2 (14.3) 0.233
Preoperative urinalysis
Positive nitrite 14 (6.1) 2 (14.3) 0.233
Positive pyuria 167 (72.9) 9 (64.3) 0.483
Positive bacteriuria 36 (15.7) 3 (21.4) 0.476
Mortality 0 (0.0) 1 (7.1)
Preoperative laboratory data
WBC (×103/ml) 7.42 (2.89-15.8) 7.42 (5.14-11.9) 0.912
Hemoglobin (g/dl) 13.4 (8.3-18.2) 12.75 (10.2-17.2) 0.629
Hematocrit (%) 39.7 (25.8-54.7) 38.7 (30.8-53.1) 0.875
Platelet count (×103/ml) 255 (14-682) 277 (213-459) 0.157
BUN (mg/dl) 15 (5-40) 16 (8-28) 0.622
Cr (mg/dl) 0.86 (0.27-5.33) 0.76 (0.24-1.97) 0.557
Albumin (g/dl) 4.30 (2.20-5.20) 4.45 (2.50-4.90) 0.377
AST (U/L) 23 (10-197) 19 (11-37) 0.349
ALT (U/L) 20 (5-96) 20 (7-114) 0.689
Na (mEq/L) 139 (130-148) 139 (135-143) 0.648
K (mEq/L) 4.0 (2.60-5.20) 4.15 (3.50-4.90) 0.265

Values are presented as median (range) or number (%).

BMI: body mass index, HTN: hypertension, DM: diabetes mellitus, IHD: ischemic heart disease, CVA: cerebrovascular disease, CKD: chronic kidney disease, Hx.: history, UTI: urinary tract infection, UPJ: ureteropelvic junction, RIRS: retrograde intrarenal surgery, PCN: percutaneous nephrostomy, WBC: white blood cell, BUN: blood urea nitrogen, Cr: creatinine, AST: aspartate aminotransferase, ALT: alanine transaminase.

*p<0.05 indicates statistical significance.

Urogenit Tract Infect 2023;18:93-100 https://doi.org/10.14777/uti.2023.18.3.93
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