Urogenital Tract Infection

Table. 2.

Studies on urine microbiome of patients with acute uncomplicated cystitis

Study population Taxa driving community structure/diversity Sample collection Technique used Ref
Adult females (92) and males (29) Some members of Enterobacteriaceae, Gardnerella, Lactobacillus, other fastidious bacteria, Candida sp., Malassezia sp. Trichomonas vaginalis; phages and HPV, Herpes sp. Mid-stream (suspected infections) 16S rRNA (V1-V3); and shotgun metagenomics [28]
Retrospective analysis, 2000–2015); 849 urine samples, all women (aged 15–65) Escherichia coli (80% of the cultures) and Staphylococcus saprophyticus Mid-stream urine Culture [25]
Adult females (38) and males (16); age range: 1–94 P: Enterobacteriaceae (No C group)
Very low diversity
Mid-stream urine 16S rRNA (V8), fimH typing of E. coli strains [29]
Adult females, 202 cases, median age 22, range: 18–49 P: Enterobacteriaceae growth was positive in 78% of midstream samples vs. 70% of catheter samples Mid-stream vs. catheterized urine samples Culture [27]
1,817 females; 300 males Females (Top 3): Ureaplasma urealyticum, Gardnerella vaginalis, Mycoplasma hominis
Males (Top 3): Ureaplasma urealyticum, E. coli, Streptococcus spp.
Suprapubic aspiration selected by midstream culture Culture [26]
Urogenit Tract Infect 2023;18:1-7 https://doi.org/10.14777/uti.2023.18.1.1
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