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Host-Pathogen Interactions in Urinary Tract Infections
Urogenit Tract Infect 2019 Dec;14(3):71-9
Published online December 31, 2019;  https://doi.org/10.14777/uti.2019.14.3.71
Copyright © 2019 Korean Association of Urogenital Tract Infection and Inflammation.

Young Hwii Ko, Jae Young Choi, Phil Hyun Song

Department of Urology, College of Medicine, Yeungnam University, Daegu, Korea
Correspondence to: Phil Hyun Song
https://orcid.org/0000-0002-3801-258X
Department of Urology, College of Medicine, Yeungnam University, 170 Hyeonchung-ro, Namgu, Daegu 42415, Korea
Tel: +82-53-620-3693, Fax: +82-53-627-5535
E-mail: sph04@hanmail.net
Received September 18, 2019; Revised October 20, 2019; Accepted November 18, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Urinary tract infections (UTIs) are classified by the host condition. Uncomplicated infections are caused most commonly by uropathogenic Escherichia coli (UPEC) and affect otherwise healthy people, whereas complicated infections are commonly caused by species, such as Proteus mirabilis, and affect patients with underlying difficulties, such as a urinary tract abnormality or catheterization. The outcome of infection caused by these bacteria is dictated by the immune response to the UTI and the host factors that influence the susceptibility to disease. This review focuses on the host pathogen interactions in UTI, including an identification of additional virulence factors and therapeutic or prophylactic targets, particularly by UPEC and P. mirabilis.
Keywords : Host-pathogen interactions; Immunity; Urinary tract infections


December 2019, 14 (3)

  • The official journal of

    The Korean Association of Urogenital Tract Infection and Inflammation

    The Korean Continence Society

    The Han-nam Urological Association

    The Korean Society of Geriatric Urological Care