search for




 

Management of Candida Urinary Tract Infection in the Elderly
Urogenit Tract Infect 2019 Aug;14(2):33-41
Published online August 30, 2019;  https://doi.org/10.14777/uti.2019.14.2.33
Copyright © 2019 Korean Association of Urogenital Tract Infection and Inflammation.

Sang Jin Kim, Jae Hyun Ryu, Yun Beom Kim, Seung Ok Yang

Department of Urology, Veterans Health Service Medical Center, Seoul, Korea
Correspondence to: Seung Ok Yang
https://orcid.org/0000-0001-8526-2023
Department of Urology, Veterans Health Service Medical Center, 53 Jinhwangdo-ro 61-gil, Gangdong- gu, Seoul 05368, Korea
Tel: +82-2-2225-1393, Fax: +82-2-2225-4374
E-mail: seungoc@hanmail.net
Received April 23, 2019; Revised May 10, 2019; Accepted May 10, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Candida urinary tract infections in elderly patients are becoming increasingly common. The risk factors for the development of candiduria include old age, use of broad-spectrum antibiotics, corticosteroids and indwelling urethral catheters, as well as diabetes mellitus, urological abnormalities, and hematological malignancies. The presence of signs and symptoms of infection are unusual, and the intensity of fungal growth in culture does not correlate with the outcome. Elderly patients often present with atypical signs and symptoms of infection. Careful assessment of the patient’s clinical status should be undertaken before treatment is initiated. The indications for antifungal therapy are the same for older and younger individuals, and the initial antifungal therapy should be selected based on the infecting organism and local epidemiology. Fluconazole is the mainstay of treatment. On the other hand, Candida glabrata is more common in elderly patients and is often refractory to fluconazole therapy. The selection of drug therapy for elderly patients should consider the comorbidities, risk of drug-drug interactions, and dose adjustment for physiological function.
Keywords : Candida; Disease management; Frail elderly; Urinary tract infections


August 2019, 14 (2)

  • The official journal of

    The Korean Association of Urogenital Tract Infection and Inflammation

    The Korean Continence Society

    The Han-nam Urological Association

    The Korean Society of Geriatric Urological Care