search for




 

Comparison of Monomicrobial versus Polymicrobial Candiduria: Time to Awareness of Candiduria
Urogenit Tract Infect 2019 Apr;14(1):20-5
Published online April 30, 2019;  https://doi.org/10.14777/uti.2019.14.1.20
Copyright © 2019 Korean Association of Urogenital Tract Infection and Inflammation.

Hyunji Kim, Mi-Kyung Lee, Tae-Hyoung Kim1

Departments of Laboratory Medicine and 1Urology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea
Correspondence to: Tae-Hyoung Kim, https://orcid.org/0000-0002-0257-3449
Department of Urology, Chung-Ang University College of Medicine, 102 Heukseok-ro, Dongjakgu, Seoul 06973, Korea, Tel: +82-2-6299-1818, Fax: +82-2-6298-8630, E-mail: kthlmk@nate.com
Received April 1, 2019; Revised April 25, 2019; Accepted April 26, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Purpose: Candiduria, which is the presence of Candida species in urine, is becoming increasingly common in hospital settings. These normal commensals in humans are often associated with the presence of other microorganisms. In this study, patients presenting with monomicrobial and polymicrobial candiduria were compared.
Materials and Methods: A retrospective study was performed on the demographic, clinical, and laboratory data of 185 patients presenting with candiduria between July 2014 and June 2015 at Chung-Ang University Hospital. The threshold for a positive Candida species urine culture was set to 103 CFU/ml. Data on the following were evaluated: distribution of Candida species; patient age and sex; length of hospital stay; presence of diabetes mellitus (DM), chronic kidney disease (CKD), a urinary catheter, and fever; antibiotic administration; urinalysis; complete blood cells; and C-reactive protein.
Results: Monomicrobial candiduria was more common (128/185, 69.2%) than polymicrobial candiduria (57/185, 30.8%). The most prevalent species was Candida albicans (monomicrobial vs. polymicrobial candiduria, 61.7% vs. 54.4%), followed in order by Candida tropicalis (18.8% vs. 24.6%), and Candida glabrata (14.8% vs. 12.3%), with no significant difference between the two groups. Significant differences in the length of stay, underlying DM or CKD, accompanying symptoms, and urine white blood cells (WBC) and bacterial counts were observed between the two groups (p<0.05).
Conclusions: The length of stay, underlying DM or CKD, accompanying symptoms, and urine WBC and bacterial counts were more associated with polymicrobial candiduria. The early detection and treatment of candiduria will become increasingly important as the Korean population ages.
Keywords : Candida; Urinary tract infections; Candidiasis; Polymicrobial infection


April 2019, 14 (1)

  • The official journal of

    The Korean Association of Urogenital Tract Infection and Inflammation

    The Korean Continence Society

    The Han-nam Urological Association

    The Korean Society of Geriatric Urological Care